I can run AC:Odyssey with Reshade on ultra and get 60 FPS.

I run EVERY other game on ULTRA with 0 stutters. I have tried a lot of INI tweaks and even use the Fallout 4 configuration tool. Then i realized that even the Vanilla game was eating RAM, well with my stupidity, i had installed a new SSD, yet i didn't run the software for it, upon doing so, i can run FO4 modded, and ofc the windows processes. I would look up 'fallout 4 ini tweaks' if that is your concern. Depending on what the contents of your mods are, they might add more processing load to the game, which usually just means more RAM usage. Generally as long as you use some kind of load order tool (like LOOT) and your mods don't have any major conflicts your game should run smoothly. There's also merging plugins, which you won't know if it works until you get ingame most of the time, and bashed patches but I don't know a thing about those. Though since you can only have so many ESPs you have to pick and choose what you want, and what you can convert to an ESL (not all can be converted smoothly). I run well over 300 plugins and my game is quite stable (a bit of recent unidentified stuttering aside). Originally posted by Sabaithal:Plugin number doesn't matter.